South West Dementia Brain Bank and DNA Bank (v4)

• Research type

  Research Tissue Bank

• IRAS ID

  320488

• Research summary

  South West Dementia Brain Bank (SWDBB)

• REC name

  South West - Central Bristol Research Ethics Committee

• REC reference

  23/SW/0023

• Date of REC Opinion

  5 Jun 2023

• REC opinion

  Further Information Favourable Opinion

• Data collection arrangements

  Brain, spinal cord (where clinically relevant) and cerebrospinal fluid are collected from deceased donors who have a diagnosis of dementia or other neurological conditions and also from older people who are not known to have been affected by these diseases. Tissue is stored and subsequently used in dementia research or research into other neurological conditions. Witnessed, informed consent is given by the potential donor or, in the case of a potential donor who is unable to give his own or her own consent, by a person in a Qualifying Relationship to the donor.

• Research programme

  Tissue donated to the South West Dementia Brain Bank (SWDBB) underpins research locally, nationally and internationally. The aim of the Bank is to support a wide range of studies on the causes, disease mechanisms, diagnosis and potential for treatment of dementia and other neurological conditions. In the last 10 years (2011-2021), the Bank has provided material that has contributed to hundreds of research papers published in peer-reviewed journals, met 276 tissue request applications and amendments, accepted 410 donations and supplied over 61,000 samples to researchers. For this reason we feel justified in calling the SWDBB an invaluable resource, which without the altruistic gift of our donors and their loved ones would simply not have been possible.

• Storage license

  12273

• RTBTitle

  South West Dementia Brain Bank (SWDBB)

• Establishment organisation

  University of Bristol

• Establishment organisation address

  Level 1, Learning & Research

  Southmead Hospital

  Bristol

  BS10 5NB