SOPHOS

  • Research type

    Research Study

  • Full title

    ScOttish Psoriatic arthritis Observational Study and biobank (SOPHOS)

  • IRAS ID

    225864

  • Contact name

    Stefan Siebert

  • Contact email

    stefan.siebert@glasgow.ac.uk

  • Sponsor organisation

    NHS Great Glasgow & Clyde

  • Duration of Study in the UK

    2 years, 11 months, 31 days

  • Research summary

    Psoriatic arthritis (PsA) is a highly varied condition, ranging from relatively mild disease limited to one area to a severe arthritis affecting most joints. However, it is not currently possible to predict how PsA will develop in an individual, making it difficult to determine optimal treatment in early disease. Early stratification of patients with PsA is becoming particularly important as new therapies become available which preferentially target specific features of the disease. In order to help address this, all adult patients in Scotland with a new or recent onset (≤4 years) diagnosis of PsA will be invited to take part in the SOPHOS national cohort. Patients will be asked to have regular clinical follow up with prospective data collection every 6 months for two years and to contribute blood samples to the linked biobank for use now and in future research projects. It is hoped the clinical and molecular results will allow early prediction of future outcomes and facilitate stratification of patients to the most appropriate treatments.

  • REC name

    London - Surrey Research Ethics Committee

  • REC reference

    17/LO/1256

  • Date of REC Opinion

    17 Jul 2017

  • REC opinion

    Favourable Opinion