SoMOSA:Study of Mechamisms of Action of Omalizumab in Severe Asthma

  • Research type

    Research Study

  • Full title

    SoMOSA: Study of Mechanisms of Action of Omalizumab in Severe Asthma.

  • IRAS ID

    183559

  • Contact name

    Ratko Djukanovic

  • Contact email

    Rd1@soton.ac.uk

  • Sponsor organisation

    University Hospital NHS Foundation Trust

  • Duration of Study in the UK

    3 years, 11 months, 30 days

  • Research summary

    In this study; we are recruiting patients who will be receiving treatment with the already licensed asthma medication - Xolair (omalizumab) routinely as part of their normal care. During their clinic visits we will be collecting data and research samples to identify biomarkers that will show which participants respond well to Xolair (omalizumab) and which participants do not. Xolair is currently licenced in the UK to treat patients with severe asthma but it is clear that not everyone with severe asthma will benefit from treatment. This data collected from the study of samples and the other tests and questionnaires may provide further information for researchers to understand the reasons why.

  • REC name

    Wales REC 5

  • REC reference

    15/WA/0302

  • Date of REC Opinion

    24 Aug 2015

  • REC opinion

    Favourable Opinion