Soft tissue changes around implants
Research type
Research Study
Full title
Dimensional soft tissue changes around implants following the use of a collagen matrix or connective tissue graft. A pilot study
IRAS ID
268553
Contact name
Nikolaos Donos
Contact email
Sponsor organisation
Queen Mary University
Clinicaltrials.gov Identifier
Clinicaltrials.gov Identifier
NA, NA
Duration of Study in the UK
3 years, 0 months, 2 days
Research summary
The main propose of this research study is to study the healing of the Gum tissue (GT) around a dental implant. Currently, there is insufficient data to indicate how much GT is needed around dental implants in order to maintain them healthy. This study will enable us to assess GT healing around implants in presence/absence of gum tissue grafts. In particular a graft taken from the patient’s own GT and a processed tissue of animal (derived from pig) origin (Fibro-Gide, Geistlich, Wolhusen) will be compared.
The GT healing process will be monitored using the following techniques:
- Intra- and extra-oral three-dimensional (3D) imaging (radiation free and contact free evaluation of volume changes);
- intra-oral thermography (radiation-free and contact free evaluation of changes in temperature);
- Laser Speckle Contrast Imaging (LSCI) - a non-invasive measurement of blood flow inside the gums;
- Dental radiographs (X-ray) and clinical assessment;
- The patients’ own reported outcomes of healing (PROMs), which include evaluation of pain experience and two questionnaires to assess how the surgery impacted on your quality of life.REC name
London - Bromley Research Ethics Committee
REC reference
20/LO/0359
Date of REC Opinion
19 May 2020
REC opinion
Further Information Favourable Opinion