Socio-economic status and prognosis in pulmonary hypertension
Research type
Research Study
Full title
Influence of socio-economic status on prognosis in Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension
IRAS ID
212169
Contact name
Martin Johnson
Contact email
Sponsor organisation
Golden Jubilee Foundation
Duration of Study in the UK
0 years, 1 months, 30 days
Research summary
Social deprivation is a measure of social well being as it relates to factors such as employment, education, and access to healthcare. Investigations into the impact of social deprivation on the course of lung disease such as Chronic Obstructive Pulmonary Disease and asthma have suggested an association between low socioeconomic status and a poorer prognosis.
Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are characterized by increasing pulmonary artery pressure and ultimately right heart failure. Despite recent advances in treatment, PAH and inoperable CTEPH remain incurable diseases associated with poor survival and high symptom burden.
The influence of social factors on the course of disease is relatively unknown. Recent studies from the USA and China suggest that social deprivation is correlated with more severe symptoms at diagnosis as well as increased risk of death.
However, this association has not been investigated in the NHS where care is free at the point of delivery. The aim of this study is to evaluate prognosis related to social deprivation in patients with PAH or inoperable CTEPH in Scotland.
REC name
West Midlands - South Birmingham Research Ethics Committee
REC reference
16/WM/0419
Date of REC Opinion
19 Sep 2016
REC opinion
Favourable Opinion