SLEEP AND TKR - 1

• Research type

  Research Study

• Full title

  Sleep quality before and after total knee arthroplasty

• IRAS ID

  208925

• Contact name

  Stylianos Papalexandris

• Contact email

  papalest@gmail.com

• Sponsor organisation

  Wirral University Teaching Hospitals

• Duration of Study in the UK

  0 years, 11 months, 30 days

• Research summary

  QUALITY OF SLEEP BEFORE AND AFTER TOTAL KNEE ARTHROPLASTY

  Osteoarthritic pain affects patients' quality of life, reduces physical activity and not infrequently impairs the structure and duration of sleep.
  
  The study will investigate 1) the incidence of sleep disturbances in patients with knee osteoarthritis warranting total knee arthroplasty, 2) whether preoperative sleep disturbances persist 4 months after total knee arthroplasty and 3) if total knee arthroplasty has a significant effect on the quality of sleep through its analgesic effect. It is anticipated that the conclusions of the study will suggest whether post total knee arthroplasty sleep disturbances need active intervention or treatment, in order for patients to engage with physiotherapy efficiently and progress with their rehabilitation uneventfully.

  Adults with advanced knee osteoarthritis undergoing total knee arthroplasty will be included in the study, which will be conducted in two NHS hospitals (Arrowe Park and Clatterbridge). The overall duration of the study is estimated to be approximately 8 months. Each participant will record a sleep diary for one week, at least 2 weeks before their surgery and 4 months postoperatively. On the same occasions, they will additionally fill in the Pittsburgh Sleep Quality Index (PSQI). Each participant is expected to be involved in the study for 6 months, even though their active contribution will be limited to two occasions, as outlined above.

  The study will gather quantitative data reflecting the duration and quality of sleep, the number of awakenings during the night and the easiness to fall asleep and getting out of bed. During hospital stay, the pain experienced by each individual will be recorded on a Visual Analogue Scale, as well as their requirements for analgesics. Comparison of the preoperative and postoperative sets of data will show to what extend total knee arthroplasty has an effect on the quality of sleep.

• REC name

  London - Fulham Research Ethics Committee

• REC reference

  16/LO/2117

• Date of REC Opinion

  30 Nov 2016

• REC opinion

  Favourable Opinion