SIPCOD (Version 1)
Research type
Research Study
Full title
Study of the role of intussusception in posterior compartment prolapse and obstructive defecation symptoms (SIPCOD)
IRAS ID
148120
Contact name
Robert Freeman
Contact email
Sponsor organisation
R and D, Plymouth Hospitals NHS trust
Research summary
Most women presenting with prolapse or weakness of the back wall of the vagina (posterior vaginal wall prolapse) have associated obstructive bowel symptoms like needing to strain to open bowel, use of laxatives, use of fingers to empty their bowels and a feeling of incomplete bowel emptying. One of the common finding in women with obstructive bowel symptoms is intussusception, where a part of the bowel telescopes on itself. An x-ray test called defecating proctogram is used to diagnose an intussusception. It is not clear whether the presence of intussusception affects the outcomes of surgery to correct the vaginal prolapse. There is also a lack of consensus and specific guidance for the management of women with posterior vaginal wall prolapse with associated bowel symptoms. This study aims to evaluate the functional outcomes (specifically the bowel symptoms) of surgery (posterior repair) for vaginal wall prolapse. The importance of intussusception (mild to moderate) is unclear and the study will compare women undergoing surgery, with and without intussusception. The study also aims to explore women’s experiences and expectations from the investigations and the surgical management through a focus group.
REC name
London - City & East Research Ethics Committee
REC reference
14/LO/0601
Date of REC Opinion
30 Apr 2014
REC opinion
Further Information Favourable Opinion