Sigmoid WISE

  • Research type

    Research Study

  • Full title

    The Sigmoid WISE Study: Surgical Anatomy and 'Waisting' of the sIgmoid SpEcimen

  • IRAS ID

    220869

  • Contact name

    Gina Brown

  • Contact email

    Gina.Brown@rmh.nhs.uk

  • Sponsor organisation

    Research & Development

  • Duration of Study in the UK

    2 years, 0 months, 1 days

  • Research summary

    Treatment of rectal cancer has improved to the extent that its local recurrence rates are now much lower than other sites in the large bowel. We have found higher rates of recurrence in the sigmoid section of the colon, just before the rectum. We believe this might be due to a narrowing in the bowel, and difficulties identifying whether cancers are in the sigmoid or rectum. We want to investigate the bowel from 20 patients undergoing surgery for left sided colorectal cancer at the Royal Marsden. These patients would have routine investigations and treatments, but once the bowel has been removed, it would undergo a MRI scan and additional slices and photography during pathological analysis.

  • REC name

    South West - Frenchay Research Ethics Committee

  • REC reference

    17/SW/0057

  • Date of REC Opinion

    15 Mar 2017

  • REC opinion

    Favourable Opinion