SIB COVacc [COVID-19]

  • Research type

    Research Study

  • Full title

    Systems Immunology and Biochemistry of Immune Responses to SARS-CoV-2 Vaccines

  • IRAS ID

    293446

  • Contact name

    Amir Gander

  • Contact email

    a.gander@nhs.net

  • Sponsor organisation

    Royal Free London NHS Foundation Trust

  • Duration of Study in the UK

    7 years, 11 months, 28 days

  • Research summary

    Understanding the immune and biochemical response to an infection is crucial to know how long immunity from infection will last and whether the correct types of immune response are being made in order to be protective (as opposed to being inflammatory and contributing to disease pathology, such as for SARS-CoV-2 and COVID-19 disease).
    Observational study to look at immune and biochemical markers in blood, sweat and saliva from people at 16 different time points before and after vaccination. With the aim of understanding the dynamics of a controlled immune response and comparing with immune responses in diseases such as COVID-19 and Ebola virus disease.

  • REC name

    East Midlands - Leicester Central Research Ethics Committee

  • REC reference

    21/EM/0064

  • Date of REC Opinion

    24 Mar 2021

  • REC opinion

    Further Information Favourable Opinion