Shoulder Pain in Cystic Fibrosis Version 1.0
Research type
Research Study
Full title
Shoulder Pain in Cystic Fibrosis
IRAS ID
339950
Contact name
CA Peach
Contact email
Sponsor organisation
Manchester University NHS Foundation Trust
Duration of Study in the UK
0 years, 6 months, 0 days
Research summary
The shoulder pain in cystic fibrosis study, aims to increase understanding of shoulder pain in this patient group. Shoulder pain is a common finding in people with cystic fibrosis but there is currently a lack of literature on this topic.
This observational study aims to gain an understanding of the most common clinical
diagnoses of shoulder pain found in this cohort of patients and if there is any common relevant clinical history.
Prevalence of shoulder pain in a 6-month period will also be recorded from those patients attending a cystic fibrosis annual review appointment at one cystic fibrosis centre.This is a non-invasive study consisting of a clinical examination and data collection. Participants will be identified by the cystic fibrosis team when patients attend their clinic appointments or identified if they have been referred to musculoskeletal physiotherapy service or if patients discuss shoulder pain with their clinical team. Posters advertising the study will be put up in clinic rooms.
The study will be discussed with identified participants, participant information leaflet given, and patients given at least 24-hour before considering to be a part of the study.
Once consented participants will be offered an appointment to co-inside with other cystic fibrosis clinic appointments and will undergoing an interview to take the history of their shoulder complaint and undergo a physical examination.
Demographic data will also be collected from medical notes on cystic fibrosis genotype, age, sex, whether they are diabetic and if so, what their recent diabetic control has been. They will also be asked to complete relevant shoulder questionnaires such as the disability arm, shoulder and hand (DASH), oxford shoulder score and a quality-of-life score (EQ-5D-5L).
Lay summary of study results: Shoulder Pain in People with Cystic Fibrosis
We looked at shoulder pain in people who have cystic fibrosis (CF). About 1 in 5 people (20%) who came for their yearly check-up had shoulder pain.
Who took part?
20 people joined the study. More than half of them (13 people) also had CF-related diabetes. 9 people had a problem called “frozen shoulder,” which makes the shoulder very stiff and hard to move.Types of shoulder pain:
We grouped the pain into three types:Type 1: Pain linked directly to CF, like CF-related joint problems or diabetes (11 people).
Type 2: Pain caused by changes in muscles and bones because of CF, like stiffness in the chest or shoulder area (3 people).
Type 3: Pain not related to CF at all (6 people).
Other findings:
12 out of 20 people had more curve in their upper back than usual (called thoracic kyphosis).
We used questionnaires to see how much the pain affected daily life. Most people did not have very high levels of disability.
However, the length of time people had shoulder pain varied a lot in the study—from 2 months to 15 years.
What does this mean?
Shoulder pain is quite common in people with CF. In this study, most participants experienced only mild symptoms that did not lead to major disability. Shoulder pain may be related to CF itself, changes in posture, or other factors.REC name
North West - Liverpool Central Research Ethics Committee
REC reference
24/NW/0069
Date of REC Opinion
5 Apr 2024
REC opinion
Further Information Favourable Opinion