Shock-wave therapy in penile rehabilitation after prostatectomy

  • Research type

    Research Study

  • Full title

    Investigating the effect of early low-intensity shockwave therapy (Li-ESWT) for preservation and restoration of erectile function after nerve sparing radical prostatectomy: a double-blind, randomized, 2-parallel-arm trial, using the Dornier Aries-2b Li-ESWT device on men aged 40-65 diagnosed with low-intermediate risk prostate cancer

  • IRAS ID

    250004

  • Contact name

    Tet Yap

  • Contact email

    tet.yap@gstt.nhs.uk

  • Sponsor organisation

    Guy's & St Thomas' Foundation NHS Trust

  • Clinicaltrials.gov Identifier

    NCT03862599

  • Duration of Study in the UK

    2 years, 0 months, 1 days

  • Research summary

    Erectile dysfunction (ED) is reported in up to 85% of men who have undergone a radical prostatectomy for prostate cancer. At present, this debilitating consequence of surgery is managed in a step-wise approach including oral medication, injections and in severe cases, insertion of a penile prosethesis. A few small studies have shown that low-intensity shockwave therapy may improve sexual performance in men with ED. However, the optimal dosage and length of treatment is yet to be determined. We propose a randomised trial evaluating the efficacy and safety of low-intensity shockwave therapy in men with ED following prostatectomy surgery.

  • REC name

    London - Queen Square Research Ethics Committee

  • REC reference

    19/LO/1534

  • Date of REC Opinion

    19 Nov 2019

  • REC opinion

    Further Information Favourable Opinion