SHINE

• Research type

  Research Study

• Full title

  Screening for Hypertension in the INpatient Environment (SHINE): A Diagnostic Accuracy Cohort Study

• IRAS ID

  252801

• Contact name

  Peter Watkinson

• Contact email

  peter.watkinson@ndcn.ox.ac.uk

• Sponsor organisation

  University of Oxford

• ISRCTN Number

  ISRCTN80586284

• Clinicaltrials.gov Identifier

  ,

• Duration of Study in the UK

  11 years, 0 months, 1 days

• Research summary

  High blood pressure (hypertension) is a major cause of illness and accounts for 12.8% of global deaths each year. If hypertension remains undiagnosed and untreated, it can become severe and difficult to treat. Many people admitted to hospital every year have undiagnosed hypertension. These patients are often discharged without treatment or a follow up plan. This might be because medical staff perceive high blood pressure in hospital to result from an acute health problem, pain or anxiousness. In addition, no research or guidelines so far have defined what is 'high' blood pressure in hospital.

  We have designed a system to screen patients in hospital for hypertension. We would like to test this and gather feedback on the system from patients and medical staff. We would also like to establish the association between high blood pressure in hospital and hypertension at home. This will guide medical staff on the best action for their patients.

  Broadly, our study questions are:
  1. What is the optimal in-hospital blood pressure level above which investigation of blood pressure at home should be undertaken
  2. Is our screening system effective and reliable?
  3. Is the system acceptable to patients and medical staff?

  We will approach hospital patients who have had regular blood pressure readings to take part in this study. We will ask them to wear a blood pressure monitor for 24 hours, approximately 4 weeks after discharge from hospital. This is because blood pressure measurements taken during usual daily activity are used to diagnose hypertension. We will then compare a person's in-hospital blood pressure measurements with 24 hours' worth of home readings. We will pool the data from 100-200 people, to analyse this at scale. At the end of the study we will ask for feedback from the people who have participated in the study and their GPs, regarding the system.

• REC name

  South Central - Oxford B Research Ethics Committee

• REC reference

  19/SC/0026

• Date of REC Opinion

  1 Feb 2019

• REC opinion

  Further Information Favourable Opinion