Scleroderma and Raynaud's Research Bank (SRRB) - 2024

• Research type

  Research Tissue Bank

• IRAS ID

  340171

• Research summary

  Scleroderma and Raynaud's Research Bank (SRRB) 2024

• REC name

  London - Fulham Research Ethics Committee

• REC reference

  24/LO/0398

• Date of REC Opinion

  12 Jun 2024

• REC opinion

  Further Information Favourable Opinion

• Data collection arrangements

  Blood samples and extracted DNA samples are stored at the Centre for Musculoskeletal Research located within the Stopford Building, University of Manchester. These are collected from patients at Salford Royal Hospital.

  Skin Biopsies are stored at the Stopford Building, University of Manchester. These are collected from patients at Salford Royal Hospital.

  Calcinosis samples are stored at the Clinical Science Building, Salford Royal Hospital. These are collected from patients at Salford Royal Hospital or by the patients themselves if they naturally extrude through the skin.

  Serum Samples are stored in the Clinical Science Building, Salford Royal Hospital. These samples are collected from patients at Salford Royal Hospital.

  Capillaroscopy and Thermography images are stored on secure servers maintained by the Northern Care Alliance NHS Foundation Trust. These images are collected from patients at Salford Royal Hospital.

  Clinical and demographic data are held on secure servers maintained by the University of Manchester and the Northern Care Alliance NHS Foundation Trust.

  Custodianship of the Bank as a whole is held by the University of Manchester and samples are held under the University's Human Tissue Authority Licence.

• Research programme

  The Bank will be used for research into scleroderma (both systemic sclerosis and localised scleroderma also termed morphoea), Raynaud's phenomenon and related disorders. Scleroderma and related disorders are rare and there is a genuine need for collaborative and multi-centre research to generate sufficient sample sizes for research into the pathogenesis and underlying disease process of scleroderma and primary Raynaud's phenomenon.

• Storage license

  12172

• RTBTitle

  Scleroderma and Raynaud's Research Bank (SRRB) 2024

• Establishment organisation

  University of Manchester

• Establishment organisation address

  Oxford Road

  Manchester

  M13 9PL