SAGE-PsA Study version 3 protocol
Research type
Research Study
Full title
Sex- And Gender-based analysis of the Effectiveness of advanced therapies in Psoriatic Arthritis (SAGE-PsA) Study
IRAS ID
326328
Contact name
Lihi Eder
Contact email
Sponsor organisation
Womens College Hospital
Duration of Study in the UK
2 years, 0 months, 0 days
Research summary
The expansion of advanced therapies that target disease-specific pathways has changed the way patients with psoriatic arthritis (PsA) are treated. However, despite the effectiveness of these therapies many patients do not achieve optimal response. Women are less likely to achieve remission, are prone to develop adverse effects and tend to discontinue treatments earlier than men. This prospective, multicenter, international cohort study recruiting 540 patients from diverse populations aims to understand how sex and gender, and their intersection with age and ethnicity, influence response to advanced therapies in PsA. This study will The results of the study will expand our understanding of the impact of sex and gender on PsA which will contribute to more personalised approach to care in this patient population.
REC name
East of England - Cambridge South Research Ethics Committee
REC reference
24/EE/0079
Date of REC Opinion
23 Apr 2024
REC opinion
Further Information Favourable Opinion