Rubidium-82 PET and Tc-99m-MIBI SPET: A head to head comparison

• Research type

  Research Study

• Full title

  Diagnosis of coronary artery disease with Rubidium-82 PET and Technetium-99m-MIBI SPET: A head to head comparison, versus coronary CT angiography.

• IRAS ID

  34314

• Contact name

  Leon Menezes

• Eudract number

  2009-016645-25

• ISRCTN Number

  n/a

• Clinicaltrials.gov Identifier

  n/a

• Research summary

  Title: Diagnosis of coronary artery disease with Rubidium-82 PET and Technetium-99m-MIBI SPET: a head to head comparison, versus coronary CT angiography. Design: A diagnostic accuracy study.Aims: To compare the diagnostic performance of Rubidium-82 PET with Technetium-99m-MIBI SPET in coronary artery disease, using coronary CT angiography as a gold standard. Outcome Measures: Sensitivity, specificity, positive and negative predictive values of each technique. Population: 102 patients clinically referred for myocardial perfusion imaging. Eligibility: Male and female (Age>40) with clinically suspected or known coronary artery disease. Treatment: Administration of Rubidium-82 and Technetium-99m-MIBI radiotracers.Duration: Up to 2 days per patient, according to BMI-determined Technetium-99m-MIBI myocardial perfusion imaging protocol.

• REC name

  London - South East Research Ethics Committee

• REC reference

  10/H1102/64

• Date of REC Opinion

  6 Dec 2010

• REC opinion

  Further Information Favourable Opinion