ROLE OF LEFT ATRIAL SITES THAT TRIGGER PULMONARY VEIN ECTOPY IN PAF
Research type
Research Study
Full title
THE ROLE OF LEFT ATRIAL GANGLIONATED PLEXI SITES THAT TRIGGER PULMONARY VEIN ECTOPY IN THE PATHOGENESIS OF PAROXYSMAL ATRIAL FIBRILLATION
IRAS ID
105573
Contact name
Prapa Kanagaratnam
Contact email
Sponsor organisation
Imperial College Healthcare NHS Trust
Research summary
Summary of Results
A total of 102 patients were analysed. 52 (51%) underwent ganglionated plexus ablation (GPA) and 50 (49%) underwent pulmonary vein isolation (PVI). There was a significantly longer duration of ablation in the PVI group compared to GPA group, and the total procedure time was significantly longer in the GPA group compared to PVI group. At the end of the 12 months follow-up, more patients in the PVI group (64%) were free from recurrence of atrial fibrillation (AF) or other types of atrial rhythm disorder, compared to patients in the GPA group (50%). However, this was not statistically significant. There was a significantly higher reduction in antiarrhythmic drug usage after GPA than after PVI. There was only one complication in the GPA group that was conservatively managed, and none in the PVI group.
REC name
London - Hampstead Research Ethics Committee
REC reference
13/LO/1150
Date of REC Opinion
9 Sep 2013
REC opinion
Further Information Favourable Opinion