Role of FCI in the detection of Proctosigmoiditis caused by IBD

  • Research type

    Research Study

  • Full title

    Role of Field-Cycling Imaging in the detection of Proctosigmoiditis caused by Inflammatory Bowel Disease (ROOFTOPS-IBD)

  • IRAS ID

    320230

  • Contact name

    Gillian Bain

  • Contact email

    gillian.bain@nhs.scot

  • Sponsor organisation

    NHS Grampian

  • Clinicaltrials.gov Identifier

    NCT05817266

  • Duration of Study in the UK

    0 years, 5 months, 8 days

  • Research summary

    Field-Cycling Imaging (FCI) is a new imaging technology being developed at the University of Aberdeen. It can image tissues non-invasively over a wide range of magnetic field strengths. Results obtained by our group in previous pilot studies have already shown that FCI provides useful information for diagnosis in a range of diseases.

    Inflammatory Bowel Disease (IBD) is a chronic condition that affects the gut in which the bowel becomes inflamed. IBD typically follows a relapsing / remitting course and, currently, it is challenging to determine its activity. FCI is, potentially, a new, non-invasive, way of assessing the extent and activity of IBD.

    In this pilot study, scans will be performed to determine the ability of FCI to detect active disease in IBD patients with proctosigmoiditis, which is an inflammation of the rectum and distal sigmoid colon.

  • REC name

    North of Scotland Research Ethics Committee 1

  • REC reference

    23/NS/0001

  • Date of REC Opinion

    28 Jan 2023

  • REC opinion

    Favourable Opinion