Rolandic Epilepsy Genomewide Association International Study (REGAIN)

  • Research type

    Research Study

  • Full title

    Rolandic Epilepsy Genomewide Association International Study (REGAIN)

  • IRAS ID

    229844

  • Contact name

    Deb Pal

  • Contact email

    deb.pal@kcl.ac.uk

  • Sponsor organisation

    King's College London

  • Duration of Study in the UK

    2 years, 11 months, 3 days

  • Research summary

    Epilepsy is a common neurological disorder affecting 1% of the population. There are over 30 types of epilepsy, some common, some rare. Most epilepsies arise in childhood and have a genetic cause. Approximately 25% of child patients have “Rolandic Epilepsy” or RE, also known as Benign Epilepsy with Centrotemporal Spikes (BECTS). RE has a complex genetic basis, probably made up of combinations of susceptibility variants in different genes. The goal of this study is to find the genetic basis for susceptibility to seizures and associated comorbidities for RE using genomewide association approaches.

  • REC name

    London - London Bridge Research Ethics Committee

  • REC reference

    18/LO/0207

  • Date of REC Opinion

    12 Apr 2018

  • REC opinion

    Further Information Favourable Opinion