REtroperitoneal SArcoma Registry (RESAR)
Research type
Research Study
Full title
REtroperitoneal SArcoma (RESAR): prospective collection of primary retroperitoneal sarcoma patient’s data, radiological and pathological material for the TransAtlantic Australasian Retroperitoneal Sarcoma Working Group
IRAS ID
299376
Contact name
Adam Barlow
Contact email
Sponsor organisation
Leeds Teaching Hospitals
Clinicaltrials.gov Identifier
Clinicaltrials.gov Identifier
ClinicalTrials.gov, NCT03838718
Duration of Study in the UK
5 years, 0 months, 1 days
Research summary
Surgery is currently the only potentially curative treatment modality for localized retroperitoneal sarcoma. Available studies regarding oncologic outcomes after surgery have been carried out, but are mainly retrospective in nature. Moreover, due to the rarity of the disease, current published data are often hampered by small patient populations. All of these limitations are reflected in the relative paucity of established guidelines and consensus statements for RPS, compared to more common malignances.
In addition, the biologic behavior, response to treatment, and clinical outcomes of RPS vary by histologic subtype and subgroup analysis are even more difficult to conduct.
Therefore, prospective analysis of high quality data is a top priority. From this perspective, building a standardized multicentric database would lead to the creation of a high quality dataset available for comparisons with previously published data and for future studies. Findings from work done using this database will help further understanding of RPS and ultimately may help to guide appropriate treatment for patients afflicted by this challenging disease.
As such, this is a prospective, multicentric observational study under the supervision of TARPSWG (TransAtlantic Australasian Retroperitoneal Sarcoma Working Group) aimed to prospectively collect clinical data from patients affected by primary RPS treated with surgery.
The database is run and maintained centrally by the study team in Milan. This application is for ethical approval for local collection of data in Leeds for patients undergoing surgery for retroperitoneal sarcoma.REC name
East Midlands - Leicester South Research Ethics Committee
REC reference
23/EM/0080
Date of REC Opinion
16 Mar 2023
REC opinion
Further Information Favourable Opinion