RETEST-STEMI
Research type
Research Study
Full title
Repeatability of myocardial oedema and strain assessment on cardiac magnetic resonance imaging following ST-elevation myocardial infarction.
IRAS ID
163853
Contact name
Gerry McCann
Contact email
Sponsor organisation
University Hospitals of Leicester NHS Trust
Duration of Study in the UK
0 years, 7 months, 31 days
Research summary
This study aims to assess the reliability of MRI scanning of the heart performed after a heart attack to detect the degree of swelling and loss of function that has occurred. MRI scanning gives us excellent pictures of the heart muscle and is the best method for detecting how much heart muscle damage has occurred. However, there is little or no information available currently on how reproducible, and therefore reliable, the information obtained is. In this pilot study we will evaluate the reproducibility of MRI in scanning on 2 different scanner types (1.5T and 3T) used at the regional heart centre, Glenfield Hospital Leicester. Twenty patients who have recently had a heart attack will be randomly allocated to be scanned on either the 1.5T or the 3T scanner and will have 2 short scans separated by a 5 minute break. This study will tell us whether there are likely to be any significant differences in the reproducibility of 1.5T and 3T scanners to detect heart muscle swelling and damage. If there are only small/minimal differences then the different scanners could be used interchangeably in the future. Additionally, up to 20ml (4 teaspoons of blood) will be taken and stored anonymously to test for new markers of heart attack/damage that may be developed in our centre.
REC name
London - Bloomsbury Research Ethics Committee
REC reference
14/LO/1917
Date of REC Opinion
21 Oct 2014
REC opinion
Favourable Opinion