Respiratory Virus Point-Of-Care Testing Pilot (ResPOC Trial) v1.0
Research type
Research Study
Full title
Point-of-care testing for respiratory viruses. Randomised controlled trial comparing POCT with standard clinical care, in adults presenting to secondary care with acute respiratory illness: a pilot study (ResPOC Trial).
IRAS ID
166069
Contact name
Tristan Clark
Contact email
Sponsor organisation
Southampton University Hospital NHS Foundation Trust
Duration of Study in the UK
1 years, 5 months, 2 days
Research summary
This study will examine the clinical impact of a point-of-care diagnostic test for respiratory virus detection (FilmArray, bioMérieux, USA; CE IVD marked) in patients presenting with acute respiratory illness, compared to routine clinical care in a pilot randomised controlled trial. Screened and consented adults with an acute respiratory illness in the Acute Medical Unit and Emergency Department of Southampton General Hospital will be randomised to either have a nose and throat swab taken and tested for respiratory viruses by POCT, or to routine clinical care alone. In the event of a virus being detected, the clinical team responsible for patient care will be informed of the result.
The clinical impact of this rapid respiratory virus detection test will assessed by measures including, but not limited to, duration of hospital stay, use of antiviral medication, use of antibiotics, use of isolation procedures/facilities and an economic analysis.
The study will take place during the typical peak season for many respiratory virus infections over winter 2014 and spring 2015, as a pilot study to provide data to inform the design of a larger randomised controlled trial planned in the near future.
REC name
North West - Preston Research Ethics Committee
REC reference
14/NW/1467
Date of REC Opinion
5 Dec 2014
REC opinion
Favourable Opinion