Reproductive aspirations of women with MRKH V2 31.08 .23. ID-290953
Research type
Research Study
Full title
Reproductive aspirations of women with MRKH
IRAS ID
290953
Contact name
Keith Boland
Contact email
Sponsor organisation
Imperial College London, Head of Research Governance and Integrity
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
Approximately 1 in 5000 females are born with an underdeveloped or absent uterus, a condition known as Mayer Rokitanksy Kuser Hauser Syndrome (MRKH). Women with MRKH have normal ovaries but the absence of the womb renders them infertile. Our team is running a clinical trial on womb transplantation whereby a donor womb from either a deceased or living donor is transplanted into the woman, IVF treatment is pursued and the woman can give birth to her own biological child. As this is a relatively new treatment to restore fertility in this group of women, we would like to investigate the enthusiasm for it. Our study is investigating the reproductive aspirations of women with MRKH. Previously only two options were available, adaption and surrogacy. Womb transplantation provides a unique third option.
All women ages over 16 years with MRKH attending the specialist NHS Gynaecology clinic at Queen Charlottes Hospital, London, will be eligible to take part in the study.
The study will run for a period of six months. Eligible women who agree to take part will be given an information sheet read and a questionnaire to complete. The overall time commitment will be ten minutes. No identifiable information will be collected and all responses will be kept anonymised.
REC name
London - Bromley Research Ethics Committee
REC reference
23/LO/0703
Date of REC Opinion
24 Aug 2023
REC opinion
Unfavourable Opinion