Recovery from Relative Energy Deficiency in Sport v3.0
Research type
Research Study
Full title
Working towards improved musculoskeletal recovery outcomes following Relative Energy Deficiency in Sport syndrome in endurance athletes
IRAS ID
327598
Contact name
Richard Blagrove
Contact email
Sponsor organisation
Loughborough University
Duration of Study in the UK
2 years, 1 months, 26 days
Research summary
Relative Energy Deficiency in Sport (RED-S) syndrome is considered a serious medical condition that can result in negative long-term health and performance consequences. Currently, the International Olympic Committee (IOC) RED-S Clinical Assessment Tool and the Safe Exercise at Every Stage guidance are used by clinicians to inform decision-making during return to training following RED-S. It has been highlighted by the IOC that research is required to establish the efficacy of specific recommendations to improve long-term recovery outcomes after RED-S. Targeting musculoskeletal-related adaptations during early-phase recovery from RED-S is a recommended strategy to mitigate against future injury and maximise return to performance outcomes, yet empirical evidence is currently lacking. The purpose of this study is to examine the effect of strength training on muscular strength, muscle morphology, and markers of bone health in endurance athletes recovering from RED-S. The study will also explore the experiences and perceptions of participants following the intervention.
The study will employ a mixed methods case-control design. A minimum of eight endurance athletes recovering from RED-S (age 16-35 years) will be required to take part. Healthy age- and sport-matched participants will also be recruited as a control group. Initially, all participants will undergo magnetic resonance imaging, dual x-ray absorptiometry, and peripheral quantitative computed tomography scans, and strength testing. Participants will also complete validated questionnaires to assess exercise psychopathology, wellbeing, and eating behaviours. A strength training intervention will then be delivered to the RED-S athletes 3 x per week for six months. Following the intervention, participants will be re-tested using identical protocols to those at baseline. Semi-structured interviews will also be used with RED-S participants to explore perceived benefits, barriers, and challenges of the intervention.
REC name
North West - Greater Manchester East Research Ethics Committee
REC reference
23/NW/0295
Date of REC Opinion
23 Oct 2023
REC opinion
Further Information Favourable Opinion