RECOVER - TAVR
Research type
Research Study
Full title
Does Cardiac REhabilitation improve functional, independence, frailty and emotional outCOmes following Trans Catheter Aortic ValvE Replacement?
IRAS ID
202909
Contact name
Paula Rogers
Contact email
Sponsor organisation
Royal Brompton and Harefield NHS Foundation Trust
Clinicaltrials.gov Identifier
Duration of Study in the UK
0 years, 10 months, 30 days
Research summary
The aortic valve is one of the four heart valves that controls the flow of blood in and out of the heart. Aortic stenosis is when the aortic valve becomes narrowed. This can cause the heart muscle to weaken and may affect the overall health and the ability to do normal daily activities.\nThe only effective long-term treatment for aortic stenosis is to replace the aortic valve. Some patients cannot have open heart surgery due to their age or other conditions that make the surgery too risky. If this is the case, some patients may be referred for a Transcatheter Aortic Valve Implantation (TAVI), which is a non-surgical alternative to open heart surgery. \nCardiac rehabilitation is a programme of exercise and information sessions to help people get back on their feet again after a heart procedure. The sessions provide patients with the information; support and advice patients need to get back to everyday life as efficiently and successfully as possible.\nWe would like to ask 30 patients who are suitable to receive the TAVI procedure to participate in a research study. The purpose of the study is to allow us to discover more about the benefit of cardiac rehabilitation in patients who have received a TAVI. It is important that we understand about the level of frailty in each of the patients before they receive a TAVI and we will assess patients by using questionnaires, testing the muscle strength in their arms and conducting a short walking test. Patients will receive their TAVI and go home when it is safe to do so. All patients will return to the out-patient clinic weeks after their TAVI procedure and we will check if they still want to be part of the study. If patients are willing to continue, we will randomise the patients to receive a cardiac rehabilitation programme or continue with normal care. We will review the patients again in clinic at three months and six months after their TAVI procedure and repeat the frailty assessment again. \n
REC name
London - Queen Square Research Ethics Committee
REC reference
16/LO/0687
Date of REC Opinion
28 Apr 2016
REC opinion
Favourable Opinion