RCT: CO THA vs Mako THA
Research type
Research Study
Full title
A prospective randomised controlled trial comparing Computerised Tomography based planning of conventional total hip arthroplasty versus Mako robotic-arm assisted total hip arthroplasty
IRAS ID
241382
Contact name
Fares Haddad
Contact email
Sponsor organisation
University College London
Duration of Study in the UK
4 years, 0 months, 1 days
Research summary
Total Hip arthroplasty (also known as total hip replacement) involve removing parts of the hip joint that have become worn out and arthritic and replacing these with artificial implants. The positioning and alignment of these artificial implants is important because they influence clinical function and implant survival. Advances in surgical technology have led to the development of computer software and robotic machines to improve implant positioning and alignment in total hip arthroplasty.
The Mako robotic machine uses x-rays and CT scan of the patient’s hip joint to calculate the amount of bone resection required and plan optimal implant position. A robotic arm then guides the surgeon during surgery to ensure that only the specified amount of bone is resected and implants are positioned correctly. In conventional total hip arthroplasty, the surgeon uses a CT scan to plan the operation and uses anatomical landmarks in surgery to guide optimal implant positioning.
The objective of this study is to compare patient recovery and accuracy of implant positioning in patients undergoing conventional total hip arthroplasty versus those receiving robotic guided total hip arthroplasty.
The study will include 60 patients with arthritis affecting the hip joint undergoing total hip arthroplasty at University College Hospital. Following informed consent, patients will be randomised into one of the two treatment groups and undergo total hip arthroplasty using either the Mako robot (Investigation group) or conventional technique (control group). All patients will receive the same rehabilitation programme following surgery. Clinical progress will be recorded at regular intervals for two years after surgery. Accuracy of implant positioning will be assessed using Computerised Tomography (CT) scanogram after surgery.
This study will enable us to determine which of the two surgical techniques in total hip arthroplasty enables faster rehabilitation, improved accuracy of implant positioning, and reduced complications.
REC name
London - Bromley Research Ethics Committee
REC reference
18/LO/0862
Date of REC Opinion
2 Jul 2018
REC opinion
Further Information Favourable Opinion