RADVILL
Research type
Research Study
Full title
Risk Acceptance for Deep Venous Interventions for the Lower Limb
IRAS ID
324000
Contact name
Robert Hinchliffe
Contact email
Sponsor organisation
Univeristy of Bristol
Duration of Study in the UK
0 years, 5 months, 31 days
Research summary
This study investigates the risk acceptance of both patients and healthcare professionals towards invasive interventions for acute iliofemoral deep vein thrombosis and post-thrombotic syndrome.
Acute deep vein thrombosis (DVT) in the long term can lead to the development of post-thrombotic syndrome (PTS) in some patients, which can significantly limit a patient’s ability to carry out daily life activities. Results from recent research studies have shown that patients with acute extensive DVT who undergo minimally invasive blood clot clearance procedures may have a lower risk of developing PTS compared to patients who only received blood thinners. In patients with established PTS, minimally invasive procedures like angioplasty (stretching/dilation of veins with balloons) and stenting (insertion of metallic mesh tubes) have shown promise in alleviating patients’ symptoms and improving quality of life, compared to routine therapies. These minimally invasive therapies are still relatively novel and are associated with additional risk of complications over and above those of standard none-invasive therapies. The purpose of this study is to investigate the risk tolerance of patients compared to clinicians towards invasive intervention for extensive DVT, and to hopefully guide shared clinical decision making in the best interest of patients’.
Patients who have had a history of acute DVT, and healthcare professionals who had experience treating acute DVT or PTS will be eligible for the study.
Participants will be interviewed via Microsoft Teams virtual meeting or telephone. A modified standard gamble method will be used to assess the risk acceptance of both patients and healthcare professionals towards invasive interventions for acute iliofemoral deep vein thrombosis and post-thrombotic syndrome. The patients and clinicians risk acceptance will be compared.REC name
HSC REC A
REC reference
23/NI/0051
Date of REC Opinion
18 Apr 2023
REC opinion
Further Information Favourable Opinion