Radial Artery Assessment in Surgical Coronary Revascularisation

• Research type

  Research Study

• Full title

  A cross-sectional study and a novel screening survey for radial artery assessment in surgical coronary revascularisation.

• IRAS ID

  333847

• Contact name

  Vincenzo De Franco

• Contact email

  vincenzo.defranco@nhs.net

• Sponsor organisation

  Royal Papworth Hospital NHS Foundation Trust

• Clinicaltrials.gov Identifier

  NCT06433960

• Duration of Study in the UK

  3 years, 6 months, 13 days

• Research summary

  The study will explore the accuracy of radial artery (RA) assessment in people with ischaemic heart disease (IHD) undergoing coronary artery bypass grafting (CABG). IHD affects 2.3 million people in the United Kingdom and is responsible for over 65,000 deaths per year (British Heart Foundation, 2023). CABG results in the most effective therapeutic strategy for multi-vessel IHD while the RA is one of the preferred graft conduits (Gaudino et al., 2018; Spadaccio and Benedetto, 2018).

  The purpose of the research is to provide an in-depth understanding of how assessment techniques inform RA harvesting, with the potential to improve surgical practice translating in better clinical outcomes and a reduced length of hospital stay.

  The study aims to answering the following research question:
  What factors influence the diagnostic accuracy of radial artery assessment in patients undergoing surgical coronary revascularisation?

  Participants for this study will include adult patients from two cardiac institutions undergoing CABG with their RA being selected as a bypass graft conduit. A cross-sectional analytic with an adaptive trial design will be used to collect data. Patients’ forearm circulation will be assessed to determine the usability of RAs. Modified Allen Test (MAT), pulse-oximetry guided MAT, Barbeau Test and ultrasonography examination will be conducted as normal measures in routine practice. A validated RA Quality Evaluation Survey will be used for assessment of the blood vessel morphology and physiology and inform decision to harvest. Follow up RA harvesting scale will be used to assess the patients’ finger mobility, cutaneous and temperature sensations.

  Main investigator initiated the study. Funding was received in support of the Professional Doctorate educational fees however funder was not involved in any part of the research topic.

  British Heart Foundation (2023) UK Factsheet. London: British Heart Foundation.
  Gaudino et al. (2018) available at: https://doi.org/10.1056/NEJMoa1716026
  Spadaccio and Benedetto (2018) available at: https://dx.doi.org/10.21037%2Facs.2018.05.17

• REC name

  South Central - Oxford B Research Ethics Committee

• REC reference

  24/SC/0076

• Date of REC Opinion

  30 Apr 2024

• REC opinion

  Further Information Favourable Opinion