Quantifying congestion by ultrasound in patients with heart failure
Research type
Research Study
Full title
Quantifying interstitial and intravascular fluid accumulation by ultrasound following temporary suspension of loop diuretics in patients with heart failure
IRAS ID
259558
Contact name
Pierpaolo Pellicori
Contact email
Sponsor organisation
NHS Greater Glasgow & Clyde
Duration of Study in the UK
0 years, 11 months, 29 days
Research summary
Heart failure will eventually affect one in every five of us; it’s often fatal. When the heart fails, the kidneys retain water (congestion), leading to symptoms, such as breathlessness and ankle swelling, requiring diuretics (water tablets). Early detection and treatment of congestion could greatly improve health and survival. We will study mechanisms leading to congestion and its quantification using non-invasive imaging and biomarkers in 20 patients with mild, stable heart failure with diuretics administered or withheld for 48 hours. The results of this research will increase the pace, robustness and precision of research leading to new ways to manage and/or prevent heart failure.
REC name
West of Scotland REC 5
REC reference
19/WS/0143
Date of REC Opinion
24 Sep 2019
REC opinion
Favourable Opinion