Quality of life outcomes after surgery for brain tumours in childhood
Research type
Research Study
Full title
Quality of life outcomes following surgical resection of brain tumours in childhood
IRAS ID
246423
Contact name
Michael Jenkinson
Contact email
Sponsor organisation
University of Liverpool
Duration of Study in the UK
1 years, 0 months, 0 days
Research summary
The aim of this study is to investigate the quality of life outcomes experienced by patients following surgical only treatment of childhood brain tumours and the impact of that surgery into adulthood.
Brain tumours are the second most common cancer in children under 15 years of age, and it has been shown that survivors of childhood brain tumours who have undergone chemotherapy and radiotherapy are at risk of adverse cognitive and psychosocial outcomes. However, there has been comparatively little assessment of the late effects and long term outcomes of childhood brain tumour patients treated curatively with surgery alone. Given the improving survival statistics of childhood brain tumours, considering these late effects of surgery is all the more important.
An observational cross-sectional study is proposed, using self-reported quality of life questionnaires for those patients aged <16 years at the time of diagnosis of a benign brain tumour, and now aged >16 years at the time of consent. The study will be administered either as postal questionnaires or during the course of routine clinic appointments.
The aim of this study is to determine the cognitive, psychosocial, health, lifestyle and functional problems experienced by patients treated with curative surgical resection alone, and to ascertain whether there is any difference in the incidence of psychosocial issues identified within patients discharged from long term follow-up compared to patients transitioned into teenage and young adult services.
REC name
East of England - Essex Research Ethics Committee
REC reference
18/EE/0225
Date of REC Opinion
25 Jul 2018
REC opinion
Further Information Favourable Opinion