Quality of Life after Gynaecological Cancer Surgery in the COVID19 era
Research type
Research Study
Full title
A single Institution Prospective Observational Study to assess Quality of Life before and after Gynaecological Cancer Surgery
IRAS ID
279102
Contact name
Alexandros Laios
Contact email
Sponsor organisation
Leeds Teaching Hospitals NHS Trust
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
0 years, 10 months, 30 days
Research summary
Little is rather known about the impact of gynaecological cancer surgery on health-related quality of life (HRQOL). Equally, evidence suggests that the level of preoperative HRQOL represents important information to be used alongside with other preoperative parameters for modern careful patient selection for surgery. We propose a longitudinal study, which will collect patient-reported outcomes (PROs) using the most widely validated cancer questionnaire at baseline (prior to surgery), 4-6 weeks post-surgery (prior to any adjuvant treatment) and at 3-months from newly diagnosed patients to explore changes over time. A sub cohort of patients with advanced ovarian, tubal and primary peritoneal cancer (aEOC) undergoing primary or delayed cytoreductive surgery will be surveyed to describe the impact on their surgical outcomes. It is intended that the study will provide detailed information about the HRQOL of gynaecological oncology patients in relation to their surgery only and not their overall treatment. The outcome data will be linked with administrative data (surgical information from hospital data). These data will be used to influence and drive service improvements, provide information to both patients and clinical teams which will allow them to make informed and appropriate treatment decisions.
REC name
South East Scotland REC 02
REC reference
20/SS/0064
Date of REC Opinion
1 Jun 2020
REC opinion
Unfavourable Opinion