Quality of Life after Acromegaly Treatment Study (QuaLAT Study)
Research type
Research Study
Full title
Quality of Life after Acromegaly Treatment Study (QuaLAT Study)
IRAS ID
243788
Contact name
Miguel Debono
Contact email
Sponsor organisation
Sheffield Teaching Hospital NHS Foundation Trust
Duration of Study in the UK
0 years, 6 months, 1 days
Research summary
Acromegaly is a slowly progressive chronic disease caused by the excessive production of growth hormone from the pituitary gland. This disease affects multiple systems of the body but is typically diagnosed after several years after which time complications such as diabetes, joint pain, and physical body changes may have become established. Consequently, the damage caused by acromegaly has been found to impact on the quality of life of the patients and persist in the long term, even after treatment.
This study will look at the population of adult patients treated for acromegaly in Sheffield Teaching Hospitals. The study will examine their quality of life (as perceived by each individual) using the validated acromegaly specific questionnaire - ACROQoL. The patient's perceptions of their health, happiness, and comfort will also be assessed using two other validated but non-acromegaly specific health questionnaires, for comparison. The quality of life of patients treated with surgery will be compared against those treated with surgery and medications, and those on medications only.
We aim to recruit 60 patients in the study. The participants will complete the consent and three medical questionnaires. All the documents will be given/posted to the patients with two return envelopes (one for the consent form, the other for the questionnaires) so they can complete the forms at home and then return to the study team. The participant with receive a reminder telephone call if the questionnaires are not returned within a month. A study doctor will complete a pro forma document for demographic information.
REC name
Yorkshire & The Humber - South Yorkshire Research Ethics Committee
REC reference
19/YH/0373
Date of REC Opinion
20 Dec 2019
REC opinion
Further Information Favourable Opinion