PUQALY. An Item Reduction Survey v5.0
Research type
Research Study
Full title
Pressure Ulcer Quality-Adjusted Life Years (PUQALY): An Item Reduction Survey
IRAS ID
125565
Contact name
Claire Hulme
Contact email
Sponsor organisation
University of Leeds
Research summary
Pressure ulcers (PUs) remain a significant healthcare problem. Approximately 1 in 10 hospital and 1 in 20 community patients will be suffering from a PU. In order to achieve the aim of eliminating pressure ulcers in NHS care there is a need for well-designed randomised controlled trials (RCTs) incorporating cost-effectiveness analyses (CEA) to identify optimal pressure ulcer interventions. CEA require the production of quality adjusted life years (QALYS). NICE states that the preferred measure for the basis of these QALYs is the EQ-5D but acknowledge it may not be appropriate in all circumstances. It is unlikely the EQ-5D will capture all domains of importance for patients with PUs. A PU Quality of Life instrument (PUQoLI) has been developed and psychometrically evaluated. It is likely a measure for use in CEA based on the items within the PUQoLI, would provide a more accurate and sensitive measure than a generic measure such as the EQ-5D, and potentially a useful tool in CEA of pressure ulcer interventions.
The aim of the overall project is to generate data using the PUQoLI in order to develop such a tool for CEA. This study will enable item reduction analysis and a comparison of item selection methods. Data will be generated via a patient survey. 100 patients with PUs will complete the interview administered measure either in hospital or in the community. Inclusion criteria are: patients aged ≥18 years and with an existing PU of any grade, location, or duration and who give their written informed consent/verbal witnessed consent. Patients will be excluded from the study if any of the following criteria apply. They: have only moisture lesions, are unconscious or confused, have cognitive impairment, do not speak or understand English, they do not have an existing PU or are unable to provide informed consent.REC name
North East - York Research Ethics Committee
REC reference
13/NE/0152
Date of REC Opinion
17 Jun 2013
REC opinion
Further Information Favourable Opinion