Pulmonary vascular disorders in Covid-19 patients [COVID-19]

  • Research type

    Research Study

  • Full title

    Pulmonary vascular disorders in Covid-19 patients

  • IRAS ID

    283311

  • Contact name

    Gerry Coghlan

  • Contact email

    Gerry.coghlan@nhs.net

  • Sponsor organisation

    Royal Free London NHS Foundation Trust

  • Eudract number

    2020-000936-23

  • Duration of Study in the UK

    1 years, 0 months, 1 days

  • Research summary

    This study is looking to see how many patients with COVID-19 have disease in their lungs that affect the blood vessels (pulmonary vasculopathy). \n\nThe study will look at three distinct groups of COVID-19 patients: those with disproportionate hypoxaemia (insufficient oxygen in the blood) ; those with thromboembolic (obstruction of a blood vessel by a blood clot ) disease; and those with inflammation of lung tissue (pneumonitis) where there is no evidence of a blood clot (thromboembolism) when a computed tomography pulmonary angiography (CTPA), a type of CT scan, is performed.\n\nThe study will also look at what impact the use of medications know as vasodilators (they open (dilate) blood vessels) have in patients with COVID-19 and evidence of vasculopathy.\n

  • REC name

    South Central - Berkshire Research Ethics Committee

  • REC reference

    20/SC/0229

  • Date of REC Opinion

    5 Jun 2020

  • REC opinion

    Further Information Favourable Opinion