Psychiatry Research and Motherhood at 6 to 8 (PRAM-P@6to8)
Research type
Research Study
Full title
Do risk factors for postpartum psychosis alter offspring outcomes in middle childhood
IRAS ID
320572
Contact name
Paola Dazzan
Contact email
Sponsor organisation
King's College London
Clinicaltrials.gov Identifier
24.03.23 v1.0, Protocol ID on clinicaltrials.gov
Duration of Study in the UK
1 years, 8 months, 29 days
Research summary
This is a follow-up study to examine the relationship between severe perinatal maternal mental illness and stress reactivity and general development of children aged 6 to 8 years. Mothers were previously recruited and assessed during pregnancy and their babies were assessed at 6 days, 8 weeks and 12 months post delivery. This follow-up will assess the occurrence of any psychiatric episodes (e.g., depression, mania, psychosis) in the intervening period. Assessments of the children will include evaluation of their response to a mildly stressful procedure, as well as their physical, cognitive and social-emotional development, and their mental health. Possible factors that may moderate the relationship between the mother's perinatal mental health and the child's stress reactivity and development, including the home environment, adversity, parent-child interaction and maternal and paternal (or co-parent) mental health will also be assessed.
REC name
London - Bloomsbury Research Ethics Committee
REC reference
23/PR/0428
Date of REC Opinion
12 Jun 2023
REC opinion
Further Information Favourable Opinion