Precision Medicine in Enlarged Vestibular Aqueduct

  • Research type

    Research Study

  • Full title

    A Precision Medicine Approach to Prognosticate Hearing Loss Associated with Enlarged Vestibular Aqueduct.

  • IRAS ID

    271326

  • Contact name

    Iain Bruce

  • Contact email

    Iain.Bruce@Manchester.ac.uk

  • Sponsor organisation

    University of Manchester

  • Duration of Study in the UK

    0 years, 11 months, 28 days

  • Research summary

    \nTitle: predicting hearing loss in children with enlarged vestibular aqueduct using artificial intelligence.\nWhy we are undertaking this research: one in every 750 children in the UK will experience hearing loss. Hearing loss can be caused by a problem of the inner ear associated with a wide bony channel (enlarged vestibular aqueduct, EVA). We know that children with EVA will develop severe hearing loss and may need a surgery to implant a hearing device but we do not know when in their life that will happen. Having a better understanding as to how hearing loss progresses in children with EVA will allow health care workers to council patients with EVA as to how often they will require hearing tests, when they will likely lose their hearing and what the best way to rehabilitate their hearing will be. \nWho will be researched: We will analyse pre-existing data from the health records of patients known to have EVA from Manchester University NHS Foundation Trust. This will be done in conjunction with data scientists at the University of Manchester.\nHow will we research EVA: We will collect pre-existing clinical, hearing loss and inner ear scan data from patients with EVA. We will use a computer programs with can learn from the data being presented to it ( artificial intelligence). We aim to test whether or not specific computer programs can learn from lots of data from our patients in order to predict how hearing loss progresses in EVA patients.\n\nThe study will last over a period of 2 years and is funded by Manchester University NHS Foundation trust and the Royal College of Surgeons.\n\n

  • REC name

    Yorkshire & The Humber - Bradford Leeds Research Ethics Committee

  • REC reference

    19/YH/0434

  • Date of REC Opinion

    16 Dec 2019

  • REC opinion

    Favourable Opinion