Pre-Pilot study of Risk of Acute Kidney Injury in Emergency Admissions

• Research type

  Research Study

• Full title

  Pre-Pilot Study to Create Model predicting Acute Kidney Injury,Death or admission to ITU after emergency admission to hospital.

• IRAS ID

  128875

• Contact name

  Simon Ball

• Contact email

  Simon.Ball@uhb.nhs.uk

• Research summary

  This is a pre- pilot study which will attempt to find factors which put patients at risk of kidney injury, death or admission to the intensive care unit when they are admitted to the hospital .These factors will then be put together to form a model that would help the emergency doctor to realize that these patients are at risk poor outcomes. The study will look at patients who are admitted to the clinical decision unit at the University Hospital Birmingham regardless of why they were admitted. Patients who are on dialysis, have had a kidney transplant or have specific blood disorders (Multiple Myeloma, Monoclonal Gammopathy of Undetermined Significance and Amyloidosis) and who are unable to speak or write English will not be asked to take part.
  The patients will be consented for blood and urine tests, in addition to the tests they would have taken routinely. Some of these samples will be stored and processed in the main study pending further ethical approval. The following information will be collected once the patients have agreed to take part in the study:
  Age, gender, racial background, list of medical problems, list of drugs taken in the past and those taken at the time of the study. Routine vital signs and blood and urine tests that are taken in hospital will also be recorded as well as additional blood and urine tests which will be taken 24 , 48 and 72 hours after the patient came into hospital.
  We will try to look at 200 patients over a three month period for the pre-pilot study. This will test the feasibility of the main study by allowing us to ensure that the study design is good and check that the consent forms and patient information are easily understood

• REC name

  North West - Preston Research Ethics Committee

• REC reference

  13/NW/0520

• Date of REC Opinion

  5 Jul 2013

• REC opinion

  Favourable Opinion