PPI-HTN Survey
Research type
Research Study
Full title
Patient Preference Information survey in patients with Hypertension
IRAS ID
279563
Contact name
Manish Saxena
Contact email
Sponsor organisation
Queen Mary University London
Duration of Study in the UK
2 years, 0 months, 0 days
Research summary
Hypertension (HTN) remains a major risk factor for cardiovascular morbidity and mortality. In majority of patients HTN is an asymptomatic disease and sometimes treating patients with pharmacotherapy can cause symptoms or side effects. In spite of established pharmacological options, a third of patients are not able to achieve good blood pressure (BP) control. This can be due to difficult to control HTN or in majority of patients it is due to poor adherence to their anti-hypertensive therapy.
Hence, there is a need for other treatment options for HTN such as device based therapies like renal nerve ablation called Renal Denervation (RDN) or through endovascular carotid sinus modulation. Studies with Recor Paradise RDN catheter system has shown promising results with good efficacy and safety in treating HTN.
Studies in the past have explored patient’s perspective and beliefs around pharmacological treatment for HTN but no previous studies have explored patient’s perspective and preferences about device based treatments for HTN. This study aims to evaluate patients’ perspective about their condition (hypertension), their quality of life (QoL), their management and how they perceive their current management. It also gets their perspective about device based treatment for hypertension using Paradise catheter system.
Patients would be shown a short video and audio clip about the procedure. They would also be given risk benefit data about the procedure before getting their perspective about this treatment. This data will help us in better understanding about patients’ preference about their management of hypertension.
REC name
London - South East Research Ethics Committee
REC reference
21/LO/0159
Date of REC Opinion
9 Mar 2021
REC opinion
Further Information Unfavourable Opinion