POS-ARI-PC
Research type
Research Study
Full title
Perpetual Observational Study (POS) of Acute Respiratory Infections (ARI) in primary care settings (PC) across Europe.
IRAS ID
324504
Contact name
Christopher Butler
Contact email
Sponsor organisation
Ecraid, University Medical Center Utrecht
Duration of Study in the UK
2 years, 11 months, 28 days
Research summary
This is a non-randomised, prospective, observational study of the presentation, management, microbiology and outcome of acute respiratory tract infection in primary care. A swab for microbiological analysis is the only additional test that participants will undergo over and above the care they would normally receive. Influenza pandemics, the current COVID-19 pandemic, and the more silent but ongoing pandemic of antibiotic resistant infections - driven partly by overuse of antibiotics for respiratory infections - all serve to emphasise that acute infections with a primary respiratory tract focus, and their treatment, continue to represent one of the greatest threats and challenges for humanity. The vast majority of acute respiratory infections (ARI) present to, and are diagnosed and managed in primary care.
Describing existing aetiology, presentation, management, and clinical outcomes and time trends for ARI in the community will help optimise care, ensure preparedness, and act as a platform for the identification and the evaluation of new intervention.The main aim for POS-ARI-PC is to provide a platform for continuous data capture for patients with ARI presenting to primary care settings across Europe, covering cases caused by known and emerging respiratory pathogens with epidemic and pandemic potential, in order to generate observational evidence to inform care and maintain study-readiness for RCT evaluations. The POS-ARI-PC platform will thereby support the efficient set-up of new clinical studies and trials, which will be embedded into the platform.
REC name
East of England - Cambridgeshire and Hertfordshire Research Ethics Committee
REC reference
23/EE/0050
Date of REC Opinion
21 Apr 2023
REC opinion
Further Information Favourable Opinion