POPStar
Research type
Research Study
Full title
Pregnancy Outcome Prediction Study: Transgenerational and Adult Review
IRAS ID
228733
Contact name
Gordon C S Smith
Contact email
Sponsor organisation
University of Cambridge
Duration of Study in the UK
11 years, 0 months, 0 days
Research summary
POPStar will be a follow-up study of the families who participated in POPS (the Pregnancy Outcome Prediction Study). POPS involved studying 4212 women who delivered their first baby in Cambridge 4-9 years ago. During their pregnancies, women attended for research scans, donated their blood and placentas for research, and allowed researchers access to the medical data surrounding their delivery. Over the last two years, we have published the results of this study that have influenced health policy and pregnancy care. For every mother who participated in POPS, we have a very highly detailed record of the pregnancy and the baby's growth in the womb
Because we know so much about the POPS pregnancies, we have a unique opportunity to understand how health in the womb influences later health outcomes. We will link information being routinely collected by national agencies (for example electronic health records, nationally-collected educational results, national disease registries) to the POPS pregnancy records to find out more about the current health status of the POPS mothers and children, and their risks of experiencing disease. This will enable us to determine how pregnancy data can be used to predict the risk of adverse health outcomes (for example high blood pressure, obesity, diabetes or learning difficulties) in both mothers and children later in life.
REC name
East of England - Cambridge Central Research Ethics Committee
REC reference
18/EE/0036
Date of REC Opinion
16 Apr 2018
REC opinion
Further Information Favourable Opinion