PoP-60
Research type
Research Study
Full title
Post-Operative Protocol 60 days
IRAS ID
325773
Contact name
Prakash P Punjabi
Contact email
Sponsor organisation
Inavya Ventures Ltd
Duration of Study in the UK
0 years, 11 months, 27 days
Research summary
Cardiovascular disease is one of the biggest health challenges in the National Health Service; although it impacts everyone with that condition, people with Black or South Asian background seem to be mostly affected primarily due to the high prevalence of diabetes; this gets further compounded by various language barriers to access health care. Imperial College NHS Trust is in West London and has a mixture of white and various ethnic minority patients.
It is vital that post-operative patients follow their treatment plan including medication and fluid intake. Project PoP-60 is a 12-month study (enrol all 25 patients and complete their follow-up) with participation by Inavya, a clinical research team from Imperial College Healthcare NHS Trust, and Ipsos. The PoP-60 study will explore whether a mobile application called ‘Avatr’ has the potential to assist patients post-elective cardiac surgery with their recovery after they have been discharged and observe the ease of patient interaction with the Avatr app. This actionable insight could enable patients to learn of the impacts associated with medication non-adherence: saving lives and money, and research how healthcare is delivered across the NHS and global markets.
Patients enrolled in the study carry on with standard care treatment and in addition as part of the research study will be using the Avatr app. Patients will enter in the Avatr mobile application several non-identifiable responses (e.g. age, gender, ethnicity etc.) and answer generic questions which could potentially support patients to improve adherence to the suggested lifestyle by their doctor and compare their responses to the national average using a colour-coded range of response for low (green), moderate (orange) and high (red) to identify risk factors.
We will approach 25 patients on day 4 of the postoperative phase (patient still hospitalised) to consider participation in the study. We will discuss the study and the possibility of using ‘Avatr’ and on day 5 upon informed consent, the patient will be part of the study group. The clinical research team will show the patient a demo of how to interact and familiarise themselves with the app to answer any questions they may have before they get discharged which is the first out of the 60 days of the study. The participants will interact with Avatr for approximately 60 days between the day of discharge and their 6-8 weeks follow-up assessment (standard of care follow-up assessment post-cardiac surgery at the hospital outpatient clinic). The patients' demographics and medication history will be shared by the participant via the Avatr app in a pseudonymised format to avoid any breach of confidentiality. Avatr will support the patients' post-discharge care plan by sending prompts and reminders to take their medication, improve their fluid intake habits and mobilise throughout the day. Also, during the same 60-day period the participants will be asked to also answer in paper version the Quality of Life, the EQ-5D-5L and the Resource use questionnaires at two separate time points: a) before they get discharged from the hospital and b) when they attend their 6-8 week follow up assessment at the hospital outpatients clinic.
Ipsos will translate the data collected by producing a health economics evaluation to better understand the potential economic impact on the NHS.
REC name
South West - Frenchay Research Ethics Committee
REC reference
23/SW/0115
Date of REC Opinion
12 Dec 2023
REC opinion
Further Information Favourable Opinion