Polygene algorithm for weight gain in first episode psychosis
Research type
Research Study
Full title
Development of a polygene-based algorithm predictive of weight gain in adults with first episode psychosis that have been prescribed antipsychotic medication
IRAS ID
239013
Contact name
Adrian Heald
Contact email
Sponsor organisation
Rotherham, Doncaster and South Humber NHS Foundation Trust
Duration of Study in the UK
1 years, 4 months, 1 days
Research summary
The purpose of the study is to determine whether a polygene-based algorithm will enable the identification of individuals at greatest risk of weight gain in the early stages of psychosis.
The study will combine existing data collected as part of routine clinical care, including weight change, medication dose and duration of treatment with a DNA sample collected by mouth swab.
If we successfully determine the value of a polygene-based algorithm in this context, consideration can be given to the use of weight neutral pharmacotherapy and lifestyle modulating strategies in this group.
REC name
South Central - Berkshire Research Ethics Committee
REC reference
19/SC/0364
Date of REC Opinion
10 Jul 2019
REC opinion
Favourable Opinion