pAToMiUM - pilot Antioxidant Therapy of Men in Unexplained Miscarriage

• Research type

  Research Study

• Full title

  The pAToMiUM Trial: pilot trial of Antioxidant Therapy of Men in Unexplained Miscarriage

• IRAS ID

  246238

• Contact name

  Jackson Kirkman-Brown

• Contact email

  J.Kirkman-Brown@nhs.net

• Eudract number

  2019-000315-91

• Duration of Study in the UK

  1 years, 8 months, 28 days

• Research summary

  A potential cause of recurrent, unexplained pregnancy loss is poor DNA quality in the man’s sperm. One prevalent hypothesis, which has never been carefully scientifically examined, is that using a minerals and antioxidants dietary supplementation may improve sperm DNA quality, in turn resulting in better reproductive outcomes. This blinded randomised controlled pilot study will assess feasibility of a full-scale trial.

• REC name

  East Midlands - Derby Research Ethics Committee

• REC reference

  19/EM/0208

• Date of REC Opinion

  9 Sep 2019

• REC opinion

  Further Information Favourable Opinion