Patient Engagement Study with Participants with AATD

  • Research type

    Research Study

  • Full title

    A Patient Engagement Study to Provide Participants with the Opportunity to Become Familiar with the Clinical Trials Unit Environment and Establish a Clinical Baseline in Adult Participants with Alpha-1 Antitrypsin Deficiency (AATD) who are Considering Participation in Future Gene Editing Clinical Trials

  • IRAS ID

    341549

  • Contact name

    Ulrike Lorch

  • Contact email

    u.lorch@richmondpharmacology.com

  • Sponsor organisation

    Beam Therapeutics Inc.

  • Duration of Study in the UK

    2 years, 8 months, 2 days

  • Research summary

    The study is being conducted to provide participants with the opportunity to become familiar with the clinical trials unit environment in adult participants with alpha-1 antitrypsin deficiency (AATD) who are considering participation in future gene editing clinical trials. The study will also allow participants to undergo a series of assessments to establish a clinical baseline (such as vital signs, ECGs, blood samples, lung function tests).

    The study will take approximately a week to complete. The study consists of a 'Day 1' visit (which involves the informed consent process, unit tour and clinical assessments) and a follow-up phone call with a Research Physician a week after the Day 1 visit. The Day 1 visit may be completed over multiple days (if required).

  • REC name

    West Midlands - Coventry & Warwickshire Research Ethics Committee

  • REC reference

    24/WM/0077

  • Date of REC Opinion

    11 Apr 2024

  • REC opinion

    Further Information Favourable Opinion