Pancreatic Surgery- pre-operative exercise programme
Research type
Research Study
Full title
The feasibility of an individualised pre-operative exercise training programme for patients awaiting pancreatic surgery.
IRAS ID
216234
Contact name
Daniel Martin
Contact email
Sponsor organisation
University College London
Duration of Study in the UK
1 years, 6 months, 0 days
Research summary
An increasing pool of evidence has shown the correlation between cardio-respiratory fitness (CRF) and perioperative outcomes. This evidence has prompted interest in the area of prehabilitation which aims to improve markers of CRF in the lead up to surgery to improve outcomes. Many of the patient cohorts studied have a relatively long preoperative window in which to implement a prehabiliation exercise programme however there has been little research into the feasibility of prehabilitation in the short preoperative time for those awaiting pancreatic resection surgery. We aim to assess the feasibility and efficacy of a supervised exercise programme in patients awaiting pancreatic resection surgery at the Royal Free Hospital (RFH). The purpose of this study is to determine whether a shorter exercise programme is sufficient to improve markers of CRF before surgery. The results from this study will be used to guide a future randomised control trial aiming to quantify the effectiveness of a prehabilitation exercise programme on post-operative outcomes in those undergoing pancreatic resection surgery.
Markers of CRF will be obtained by cardio-pulmonary exercise testing (CPET) at baseline and after approximately 4 weeks of exercise training. Those in the intervention group will attend three 30-40 minute exercise sessions a week consisting of interval training on a cycle ergometer. Markers of fitness obtained via CPET will guide the intensity of these training sessions. Those in the control group will complete a CPET at baseline and week four but will not complete the exercise intervention. Both groups will complete quality of life questionnaires at the beginning and end of the study and Daily physical activity will be monitored using an activity monitor provided.
REC name
London - Stanmore Research Ethics Committee
REC reference
17/LO/0403
Date of REC Opinion
30 Mar 2017
REC opinion
Further Information Favourable Opinion