PANACEA Trial
Research type
Research Study
Full title
Prospective, Randomised, Crossover, Controlled, Feasibility Study to Assess the Efficacy of BurstDR Spinal Cord Stimulation (SCS) as a Treatment for Persistent AbdomiNal RefrActory VisCEral PAin Secondary to Chronic Pancreatitis: PANACEA Trial
IRAS ID
212921
Contact name
Ganesan Baranidharan
Contact email
Sponsor organisation
Leeds Teaching Hospitals NHS Trust
Clinicaltrials.gov Identifier
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
To evaluate the effectiveness of BurstDR stimulation as a treatment for persistent abdominal refractory visceral pain secondary to chronic pancreatitis. Abdominal pain is a main symptom in patients with chronic pancreatitis. Patients have a background constant pain with acute episodes needing admissions.
Spinal cord stimulation (SCS) is a recognised treatment for neuropathic pain. This involves placing an electric wire in the spine and the use of electricity to manage the pain. This is a pacemaker for controlling pain. BurstDR stimulation delivers a wave form which mimics the way nerves conduct electrical signals, there are short bursts or spikes of stimulation followed by short periods of rest.
The key aims and objectives of this study are to evaluate the efficacy of BurstDR SCS as a treatment for persistent pain secondary to chronic pancreatitis.REC name
South West - Cornwall & Plymouth Research Ethics Committee
REC reference
18/SW/0044
Date of REC Opinion
1 May 2018
REC opinion
Further Information Favourable Opinion