P-ICECAP
Research type
Research Study
Full title
Paediatric Influence of Cooling duration on Efficacy in Cardiac Arrest Patients
IRAS ID
319551
Contact name
Hari Krishnan
Contact email
Sponsor organisation
Birmingham Women's and Children's NHS Foundation Trust
Clinicaltrials.gov Identifier
Duration of Study in the UK
4 years, 11 months, 31 days
Research summary
The goal of P-ICECAP is to find out if cooling improves outcomes following resuscitation from cardiac arrest in children under 18 years of age. Experimental evidence and evidence from newborn babies suggests this is an effective therapy. However, paediatric and adult studies have not shown effectiveness conclusively. This may be because the chosen depth or duration of cooling may have been inadequate. In this study children are either cooled for different durations or maintained at normal temperature to prevent fever. Other than duration of temperature control, children in the study get the same care for cardiac arrest in Paediatric intensive care units. The study is funded by the National Institute of Health, USA. About 900 children will be enrolled at about 60 hospitals in the US and multiple additional sites across the world including the UK, Canada, Australia and New Zealand.
REC name
South Central - Berkshire Research Ethics Committee
REC reference
24/SC/0376
Date of REC Opinion
8 Jan 2025
REC opinion
Further Information Favourable Opinion