Oximetry parameters in children with cyanotic congenital heart disease
Research type
Research Study
Full title
A study to assess normal oximetry values in children under the age of 12 years with cyanotic congenital heart disease.
IRAS ID
224598
Contact name
Hazel Evans
Contact email
Sponsor organisation
University Hospital Southampton NHS Foundation Trust
Duration of Study in the UK
2 years, 6 months, 1 days
Research summary
The prevalence of obstructive sleep apnoea in children is between 1 and 2%. Pulse oximetry is frequently used as a first line investigation for detecting obstructive events. Modern pulse oximeters using Masimo technology (Masimo USA) have the ability to eliminate motion artefact as well as to generate key oximetry parameters for detecting obstructive sleep apnoea. One of the key indices used to detect significant events is the number of desaturations greater than 3 and 4% per hour and normal oximetry values have been reported for typically developing school age children. However indices that are applicable in typically developing children are not necessarily relevant to children with cyanotic congenital heart disease. This is because baseline saturations are lower so potentially children will have a greater tendency to have dips in oxygen levels with small changes in breathing pattern. No normal data is available for this group of children. This will be a pilot study following which we hope to undertake a definitive study. This study aims to collect data on around 30 healthy children with cyanotic congenital heart disease to obtain information on oxygen saturations overnight using home pulse oximetry when they are well. This will assess feasibility for undertaking a larger study identifying normal oxygen parameters in children with cyanotic heart disease
REC name
London - Dulwich Research Ethics Committee
REC reference
17/LO/1462
Date of REC Opinion
25 Sep 2017
REC opinion
Further Information Favourable Opinion