OUTREACH study: Urine analysis and antihypertensive treatment
Research type
Research Study
Full title
BiOmarkers in Urine, anTihypeRtensive trEAtment and blood pressure Control in Hypertensive patients - OUTREACH Study
IRAS ID
229352
Contact name
Laurence Loubiere
Contact email
Sponsor organisation
University of Manchester
Clinicaltrials.gov Identifier
Duration of Study in the UK
3 years, 0 months, 0 days
Research summary
High blood pressure (also called hypertension) is a condition that affects more than 1 in 4 adults. It can strain the heart and the blood vessels, and increase the risk of stroke, heart attack, heart failure, kidney damage, and death. Failure to take medication as prescribed (i.e. non-adherence) is believed to be common in hypertension because it rarely has noticeable symptoms. The patients recruited in this study will be asked to provide a urine sample at the hypertension clinic to find out if they take their blood pressure medication as prescribed. A group of non-adherent patients will participate in a simple 5-step (Discuss/Explore/Act/Co-operate/Reinforce) intervention in which the patient and the treating doctor will discuss the test result, the reasons for not taking the medication as prescribed, and useful measures to improve adherence.
Our aim is to test if the 5-step intervention helps non-adherent patients to comply with their treatment and lower their blood pressure. Adherence, health outcomes and care costs will be measured and compared with groups of non-adherent and adherent patients who did not receive the intervention.REC name
North West - Greater Manchester South Research Ethics Committee
REC reference
17/NW/0637
Date of REC Opinion
20 Dec 2017
REC opinion
Further Information Favourable Opinion