Oral vitamin D and cardiovascular risk in UK south Asians - version 1
Research type
Research Study
Full title
The effects of oral vitamin D supplementation on cardiovascular disease risk in UK south Asians
IRAS ID
5727
Contact name
Faisal Khan
Contact email
Sponsor organisation
University of Dundee (to be confirmed)
Eudract number
2008-003387-18
ISRCTN Number
Pending
Research summary
Vitamin D deficiency is associated with important risk factors for heart and blood vessel (cardiovascular) disease. Low levels of vitamin D have been linked to glucose intolerance, insulin resistance and inflammatory chemicals in the blood, which can worsen the consequences of cardiovascular disease and diabetes. South Asians living in the UK are particularly at risk of developing cardiovascular problems and diabetes. They also have especially low levels of vitamin D, probably due to a greater requirement for exposure of the skin to sunlight (the main'source of vitamin D). The aim of this project is to investigate whether giving supplementary vitamin D to UK south Asians will improve cardiovascular function, decrease insulin resistance and decrease levels of inflammatory chemicals. Early treatment with vitamin D supplementation could prove to be a relatively simple, cheap and effective way of reducing risk of cardiovascular disease and type 2 diabetes in later life
REC name
East of Scotland Research Ethics Service REC 1
REC reference
08/S1402/55
Date of REC Opinion
22 Oct 2008
REC opinion
Further Information Favourable Opinion