ORACLE
Research type
Research Study
Full title
ORACLE: Objective risk assessment in patients with possible anginal chest pain using leading technology
IRAS ID
337367
Contact name
Michael McDermott
Contact email
Sponsor organisation
University of Edinburgh
Duration of Study in the UK
0 years, 6 months, 0 days
Research summary
Recent onset angina is a manifestation of unstable or progressive coronary artery disease and is a common presentation within primary care. Evaluation is challenging as access to objective measures of risk and diagnostic testing are limited in this setting. Due to capacity, not all patients referred to the rapid access chest pain clinic can be reviewed within this clinic and patients, previously known to a cardiologist, may be referred back to consultant cardiologist that assessed them within the past 5 years. Patients referred on for cardiology consultant review are often highest risk with known obstructive coronary artery disease, previous coronary artery bypass surgery or previous coronary artery stents and they often wait longer to be reviewed relative to patients seen at the rapid access chest pain clinic.
This feasibility study has been designed to deliver a virtual chest pain assessment for patients with new onset chest pain, that uses a combination of digital tools to capture relevant patient information and clinical history, point-of-care high-sensitivity cardiac troponin testing and electrocardiography. This pathway will aim to provide an objective assessment of risk on the next working day following primary care contact to all patients referred to the rapid access chest pain clinic.
On completion of this assessment patients will be stratified to low, intermediate or high risk groups based on their symptoms, risk factors, point of care troponin value (ng/l) and ECG. The results will not be made available to the patient or clinical team unless the patients was at risk of harm (acute coronary syndrome or arrhythmia). Patients will return to receive routine clinical care.
We plan to recruit 300 participants or for six months, whatever arises first. Participants can only be recruited once during the study period.
REC name
North of Scotland Research Ethics Committee 2
REC reference
24/NS/0021
Date of REC Opinion
22 Mar 2024
REC opinion
Further Information Favourable Opinion